Against Breast Cancer funds groundbreaking cancer research to improve detection, treatment and increase survival after breast cancer diagnosis. The focus of our research is preventing secondary spread, the main cause of breast cancer related deaths.
The ultimate goal of Against Breast Cancer is to stop secondary breast cancer from claiming lives. Our unique approach is to do this by focusing our research on three key areas: prevention, detection and therapies.

Alder Hey Children’s Charity is an independent charity which supports Alder Hey Children’s NHS Foundation Trust to make a difference for the 450,000 children and young people who use the hospital’s services every year. Since 2013, over £82 million has been raised to support patients and their families through our pillars of Equipment, Research, Innovation and Education, Campus and Community, Magic and Advocacy. Together, we work to build brighter, happier, healthier and fairer futures for all children and young people.

Alzheimer’s Research UK is the UK’s leading dementia research charity. We’re working to revolutionise the way we treat, diagnose and prevent dementia. But we will not stop there. With your support, we will keep going until every person is free from the heartbreak of dementia. We exist for a cure.

The Brain Tumour Charity is the world’s leading brain tumour charity and the largest dedicated funder of research into brain tumours globally. Committed to saving and improving lives, we’re moving further, faster to help every single person affected by a brain tumour. We’re set on finding new treatments, offering the highest level of support and driving urgent change. Because we understand that when you, or someone you love, is diagnosed with a brain tumour – a cure really can’t wait.

The British Red Cross helps millions of people in the UK and 190 countries around the world get the support they need when disaster strikes. Our UK teams help people home from hospital, provide specialist mobility equipment, support refugees, vulnerable migrants and victims of human trafficking and aid people in emergencies from house fires to major flooding. Internationally, we partner with our sister societies to prevent and ease human suffering. Together, we are the world's emergency responders.

We’re the Campaign Against Living Miserably (CALM) and we’re taking a stand against suicide. That means standing against feeling hopeless, standing up to stereotypes and standing together to show life is always worth living.

Our vision: A future in which nobody believes suicide is their only option.

Our mission: To help people end their misery not their lives.

We are Scotland’s largest health charity working to help people with chest, heart, and stroke conditions live life to the full. Everyone should have the right to live life to the full after a stroke or diagnosis of a chest or heart condition. Many people living with our conditions experience fear, isolation and loneliness, and struggle to cope with the impact of their health condition on their everyday lives. But our amazing nurses, support workers and volunteers are here to make sure no one must recover alone.

Deafblind UK is a national charity dedicated to supporting the estimated 450,000 people affected by sight and hearing loss in the UK. We believe that every person who is deafblind should be able to live the life they want, empowered through holistic care and assistance, pioneering research, transformative education, influential advocacy, and innovative technology integration. By running for Deafblind UK, you will be ensuring that everyone facing sight and hearing loss has the support they need.

Freedom from Torture is dedicated to healing and protecting people who have survived torture. We stand with survivors, providing therapy and support, and fighting for change together. We provide therapies to improve physical and mental health, we medically document torture and we offer legal and welfare help. We fight to hold torturing states to account and we campaign for fairer treatment of survivors in the UK. Therapeutic, creative and social groups offer activities from gardening and breadmaking to football and chess.

It’s Time was founded from lived experience, knowing firsthand the impact of losing a parent as a young adult. 1 in 7 people will face this life-changing loss by the age of 30, yet the challenges that come with it are often overlooked. We created It’s Time to offer connection, understanding, and support through peer support, grief education, and free group therapy, helping young adults navigate grief, find community, and rebuild hope for the future.

Kidney Care UK is the leading kidney patient support charity in the UK, dedicated to improving the lives of people affected by kidney disease. For 50 years, we've provided practical, emotional and financial support to thousands of patients and their families. From advocacy and grants to counselling and peer support, we work to ensure no one faces kidney disease alone. We’re committed to raising awareness, improving care and giving patients a stronger voice across the UK.

Manchester Foundation Trust Charity raises funds to support Manchester University NHS Foundation Trust’s family of ten hospitals, which includes Royal Manchester Children’s Hospital, Wythenshawe Hospital, Manchester Royal Infirmary and Saint Mary’s Hospital. Our patients are at the heart of everything we do. We raise funds to make a difference for patients, young and old, cared for in hospitals by making sure that they receive the very best treatment in the very best facilities.

Marie Curie supports anyone with a terminal illness and their loved ones. Whatever the illness, wherever you are, Marie Curie is with you to the end. With 75 years of experience and leading research, we provide care at home, in hospices, and over the phone. We campaign and share research to improve end-of-life care for all; and as a UK-wide charity, we need your support to continue our vital work.

Make-A-Wish UK is part of a global movement creating life-changing wishes. Our only goal is to give children facing critical illness the chance to dream big even when they might not have long to live. No matter what the future holds, we create lasting memories families will treasure forever.​

Médecins Sans Frontières/Doctors Without Borders (MSF) delivers emergency medical care where it’s needed most. Whether it’s conflict zones, natural disasters, or disease outbreaks, MSF teams race to save lives. Independent and impartial, MSF helps people regardless of race, religion, or politics, by providing both basic and complex medical care. MSF’s goal is to relieve suffering, reduce the spread of diseases, improve access to healthcare and save lives.

We produce trusted information all about mental health problems. We support people through our helplines and online Side by Side community. We campaign with the government to get a better deal on mental health. And we speak out when something isn’t right, demanding mental health support respects our rights. There’s so much we do – and we couldn’t do it without you, so thank you.

People with a learning disability have long been discriminated against and disproportionately affected by cuts to government funding. We operate around 650 services, and provide personal support to 4,000 people each year.

Our vision is for the UK to be the best place in the world for people with a learning disability to live happy and healthy lives. We do this by: Providing services, Campaigning, Empowering people to create change in their communities, Helping people to gain employment, Offering people information and advice, Researching into important issues

The MND Association is the leading charity in England, Wales and Northern Ireland focused on funding research, improving access to care and campaigning for people living with or affected by MND. We fund and promote research that leads to new understanding, treatments and brings us closer to a cure. We campaign and raise awareness so the needs of people with MND are recognised and addressed by wider society. People with MND, their families and carers are at the heart of everything we do.

Mustard Tree has been combatting poverty and preventing homelessness across Greater Manchester for over 30 years. We provide frontline services to our community through our Food Club, Community Shop, 1-1 support, advocacy, and hardship gifting. These frontline services run alongside our pathways out of poverty including The Freedom Project, vocational courses, English provision and creative classes. This holistic, wraparound approach enables service-users to increase their long-term stability and break out of the cycle of poverty.

The North West Air Ambulance Charity’s helicopters and critical care vehicles operate 365 days a year. Their highly skilled doctors and critical care paramedics on board provide enhanced pre-hospital care to patients across the entire North West region each year – an area covering 5,500 square miles and over 8 million people.  

The charity is not part of the NHS and doesn’t receive any government funding. They rely completely on public and corporate donations to carry on saving lives.

Oxfam is a global community of people who believe in a kinder, and radically better world, where everyone has the power to thrive not just survive. We believe we can overcome poverty by fighting the injustices and inequalities that fuel it.

The Paget’s Association is the only UK charity dedicated solely to Paget’s Disease of Bone. Often misunderstood, the condition can cause pain, fractures and bone deformity. We raise awareness, fund vital research and provide trusted support to patients, carers and health professionals. By joining our team for the Manchester Marathon, you’ll help improve lives and advance understanding of Paget’s disease. Each step and every pound raised helps raise awareness, transform lives and fund vital progress.

Pancreatic cancer is the deadliest common cancer. More than half of people die within three months of diagnosis. When you fundraise with us, you’re supporting vital, world-leading research. You’re ensuring our nurses are there to take more calls. And you’re driving our campaigns to make sure pancreatic cancer gets the attention it deserves. You’re giving people more than hope to hold onto.

We’re Parkinson’s UK, the charity that’s here to support every Parkinson’s journey. Every step of the way.

Place2Be is the UK's leading provider of school-based children's mental health services, and our mission is to improve the mental wellbeing and prospects of children, their families and school communities. We reach nearly 300,000 children and young people in around 500 partner schools, working with pupils, families, and staff in a whole-school approach. We have been instrumental in contributing to the breakdown of stigma of mental health within schools and in advocating for the integration of mental health support into the school environment.

Refuge is the country’s largest provider of specialist domestic abuse services for women and their children and opened the world’s first safe house in 1971. We now provide a range of services including but not limited to; safe house refuges for survivors and their children, a National Domestic Abuse Helpline which is available 24/7 365 days of the year for anyone experiencing or worried about someone experiencing domestic abuse, community outreach services, and culturally specific services.

Join Rethink Mental Illness at the Manchester Marathon and help change lives! We’re working tirelessly to transform mental health support. By joining Team Rethink you’ll empower people living with mental illness to get the care, respect, and opportunities they deserve. Every step raises awareness and vital funds for advocacy, crisis support, and life-changing services. Together, we’re breaking stigma and building a future where no one faces mental illness alone. Run for Rethink and you will run for change!

Run for Charity work with thousands of charities all over the UK.  If you have a particular cause you'd like to run for, there is a good chance they are here, and they would love your support!

At Sense we believe no one, no matter how complex their disabilities, should be left out of life. Our goal is to support ten times more people living with complex disabilities by 2026

We work to support anyone affected by pregnancy loss or the death of a baby. We also carry out vital work to improve maternity safety through targeted research, campaigning for change, working with government and reducing inequalities in healthcare to save babies' lives. Our vision is for a world where fewer babies die and when a baby does die anyone affected receives the best possible care and support for as long as they need.

Samaritans is the only emotional support service open 24 hours a day, 365 days a year, to anyone across the UK and Ireland. Every year we receive over 5 million calls for help, across our 201 branches. When people get in touch, we listen – in confidence and without judgement. Whether it’s online, over the phone or face-to-face, we give people the space and time to work through their problems in their own way.

We believe that everyone deserves to have the best quality of life possible. We aim to meet the unique physical, emotional, social and spiritual needs of those with a life-limiting illness, and to help maintain their dignity. We provide specialist palliative care for people with cancer and non-cancer life-limiting illnesses, at all stages of their illness. We recognise that it’s also a difficult time for relatives, carers and friends and we provide support for them too.

At Target Ovarian Cancer, we target what’s important to stop ovarian cancer devastating lives.  We're the only ovarian cancer charity working across all four nations of the UK. We work with everyone affected by ovarian cancer and health professionals to ensure we target the areas that matter most for them.

We’re Tommy’s: a charity that exists to stop the heartbreak and devastation of baby loss and make pregnancy and birth safe – for everyone. Bringing together a network of researchers, healthcare professionals and passionate supporters, Tommy’s is a community.